Prediction of pulmonary complications and long-term survival in systemic sclerosis.

Author: Nihtyanova SI, Schreiber BE, Ong VH, Rosenberg D, et al
Date Published: June-2014
Source: Arthritis & Rheumatology

Abstract - OBJECTIVE: To assess survival and incidence of organ-based complications in a large single-center cohort of unselected systemic sclerosis (SSc) patients, and to explore predictors of survival and clinically significant pulmonary fibrosis (PF) and pulmonary hypertension (PH). METHODS: The study cohort consisted of 398 consecutive SSc patients, followed up for up to 15 years. Cox proportional hazards analysis with demographic, clinical, and laboratory characteristics as predictor variables was used to develop prediction models for pulmonary complications and survival.