Where does scleroderma come from and who gets scleroderma?

Scientists don’t yet have a complete understanding of what causes scleroderma, but they are working hard to unravel the mystery, find better treatments and a cure. Anyone can get scleroderma, anywhere in the world and at any age. Women seem to be diagnosed with scleroderma more frequently than men. In fact, women with the disease outnumber men with it by about four-to-one. Many people show signs of the disease at middle-age.