Localized Scleroderma Characterized by T-Cell Cytokines and Chemokines

Author: Maureen Newman
Date Published: December-2014
Source: Scleroderma News

New Scleroderma-related findings have linked two variations of the disease, which in turn could lead to effective, new biomarkers and targeted treatments for patients. Two clinically different diseases, localized scleroderma (LS) and systemic sclerosis (SSc), can be characterized by similar T-cell produced cytokines and chemokines in pediatric patients, according to recent work presented at the 2014 American College of Rheumatology. At the meeting, Dr. Kathryn S. Torok, from the Pediatric Rheumatology Department of Children’s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, presented “Circulating T-Helper Cell- Associated Cytokines and Chemokines in Localized Scleroderma,” which delved further into the biological characteristics of the only partially-investigated disease LS.