ZEBRA Clinical Trial Testing Treatment for Scleroderma Renal Crisis

Author: Maureen Newman
Date Published: January-2015
Source: Scleroderma News

“Zibotentan Better Renal Scleroderma Outcome Study (ZEBRA)” is more than a standard clinical trial for scleroderma patients. Rather, the phase 2 clinical trial is a three-part clinical trial seeking to help patients with mild, moderate, or severe kidney disease due to scleroderma. University College, London is sponsoring the trial in collaboration with the Medical Research Council. The aim is to study Zibotentan in patients with mild or moderate kidney disease in ZEBRA 1, severe acute kidney disease (renal crisis) without dialysis in ZEBRA 2A, and renal crisis with dialysis in ZEBRA 2B.