PFTs Often Miss Lung Disease in Scleroderma

Author: Wayne Kuznar
Date Published: September-2015
Source: MedPage Today

Pulmonary function tests (PFTs) are not reliable for the detection of scleroderma interstitial lung disease (SSc-ILD), results of a prospective cohort study suggested. An international team of researchers found that only one-fourth of patients with scleroderma had a forced vital capacity (FVC) <80% and only about half had an abnormally low value in at least one PFT. Further, almost two-thirds of patients with significant ILD on high-resolution computed tomography (CT) had a normal FVC.