Relationship between Body Mass Composition, Bone Mineral Density, Skin Fibrosis and 25(OH) Vitamin D Serum Levels in Systemic Sclerosis

Author: A. Corrado, R. Colia, A. Mele, V. Di Bello, A. Trotta, A. Neve, F. Paolo Cantatore
Date Published: September-2015
Source: PLOS One

Systemic sclerosis (SSc) is a rare chronic autoimmune disease characterised by an increased synthesis and deposition of extra-cellular matrix in skin and internal organs and widespread macro and micro- vascular damage. Depending on the extent of skin fibrosis, SSc can be classified in two main subtypes, the limited cutaneous form (lcSSc) and the diffuse cutaneous form (dcSSc) [1].