New Phase III Study of Nintedanib in people with Systemic Sclerosis and Lung Fibrosis

Date Published: December-2015
Source: BI

Boehringer Ingelheim announced today that the first person has been enrolled in the SENSCIS™ (Safety and Efficacy of Nintedanib in Systemic SClerosIS) study. The global Phase III trial, which is now open for recruitment, is investigating the efficacy and safety of nintedanib in people with a rare disease called systemic sclerosis (SSc) who also developed interstitial lung disease (SSc-ILD) (NCT02597933).1 In total, 520 people are expected to be enrolled in clinical trial centres worldwide. Systemic sclerosis, also known as scleroderma, is a rare disease characterised by the thickening and scarring of connective tissue of multiple organs in the body.2 The scarring can also affect the lungs and when this occurs the condition is called SSc-ILD.2 The presence of ILD with SSc often indicates a poor prognosis and higher risk of death.