New Biomarker Assay to Aid in Systemic Sclerosis Diagnosis

Author: Dainela Semedo
Date Published: December-2015
Source: Scleroderma News

Protagen AG, a leader in the development of novel molecular diagnostics for autoimmune diseases, recently launched the Multilisa BICD2, an ELISA (enzyme-linked immunosorbent assay) that together with clinical symptoms will aid on the diagnosis of systemic sclerosis (SSc). SSc is a complex, multi-organ autoimmune disease characterized by increased fibroblast activity that results in abnormal growth of connective tissue, causing vascular damage and fibrosis. Fibrosis can occur in the skin, the gastrointestinal (GI) tract and other internal organs. The clinical manifestations of SSc are extremely heterogeneous and dependent on the presence and degree of organ involvement. SSc is a rare disorder, with an annual incidence in the United States of about 20 cases in every 1 million adults.