Estrogen Likely Contributes to Cold-induced Raynaud’s in Women

Author: Magdalena Kegel
Date Published: February-2017
Source: Raynauds

Estrogen may contribute to the development of Raynaud’s phenomenon in women, according to a study examining the relationship between palm blood flow and the hormone in mice. The findings might explain why Raynaud’s is more common in women of childbearing age. The study noted that reduced blood flow was mediated by estrogen’s effects on cell surface receptors. The study, “G-protein coupled estrogen receptor-mediated non-genomic facilitatory effect of estrogen on cooling-induced reduction of skin blood flow in mice,” was published in the European Journal of Pharmacology.