Digital Ulcers Predict Systemic Sclerosis Complications

Author: Nancy Walsh
Date Published: December-2015
Source: MedPage Today

Patients with systemic sclerosis (SSc) who have chronic digital ulcers experience high rates of severe complications and medication use, a retrospective European study found. Among a cohort of almost 1,500 SSc patients who either had a history of digital ulcers or ulcers present at the time of enrollment and who were followed for 2 years, gangrene and amputation were reported in 22% and 15.9% of those who had ulcers present at each follow-up clinic visit compared with 1.5% for both outcomes among patients who had no new ulcers at any study visit, according to Marco Matucci-Cerinic, MD, of the University of Florence, and colleagues.