2017-2018 Funded Research

 

RESEARCH GRANTS: Total Awarded: $1,723,880*

InvestigatorInstitutionResearch Project(s)
Livia Casciola-Rosen, PhD
Professor of Medicine

Zsuzsanna McMahan, MD, MHS
Assistant Professor of Medicine
Johns Hopkins University School of Medicine

Autoantigen Discovery in Scleroderma Subsets: Possible Targeting of the Neural Crest in Patients with Severe Gastrointestinal Disease

Livia Casciola-Rosen, PhD
Professor of Medicine

Ami Shah, MD
Assistant Professor of Medicine
Johns Hopkins University School of Medicine

Defining Novel Autoantibodies and Associated Cancer Mutations in Scleroderma

Howard Chang, MD, PhD
Professor of Dermatology

Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford University School of Medicine

Gene Regulatory Mechanisms in Scleroderma

Epigenetic Investigation of Twins Discordant for Scleroderma**

Epigenetics of Sex Differences in Scleroderma

Lorinda Chung, MD, MS
Associate Professor of Medicine Division of Immunology and Rheumatology

Paul Wolters, MD
Associate Professor of Medicine
Pulmonary and Critical Care Medicine

Stanford University School of Medicine




University of California, San Francisco

Northern California Scleroderma Research Consortium

Lorinda Chung, MD, MS
Associate Professor of Medicine Division of Immunology and Rheumatology

David Fiorentino, MD, PhD
Associate Professor of Dermatology
Division of Immunology and Rheumatology

Stanford University School of Medicine Stanford Scleroderma Center of Excellence
Hal Dietz, MD
Victor A. McKusick Professor of
Genetics and Medicine, Investigator, HHMI
Johns Hopkins University School of Medicine; Howard Hughes Medical Institute Interrogation of the Pathogenesis of Stiff Skin Syndrome: A Congenital Form of Scleroderma
Monique E. Hinchcliff, MD
Assistant Professor of Medicine
Northwestern University Feinberg School of Medicine DNA Microarray of Skin Biopsies and Traditional SSc Biomarkers: Does Microarray Analyses Provide Additional Prognostic Information?

David Lagares, PhD 
Director of the Matrix and Mechanobiology Program 

Massachusetts General Hospital and Harvard Medical School

 

Biomechanical and Biochemical Drivers of Scleroderma Fibrogenesis: Targeting Myofibroblast Resistance to Apoptosis to Reverse Established Fibrosis
Ruslan Medzhitov, PhD
Sterling Professor of
Immunobiology, Investigator, HHMI
Yale University Macrophage-stromal Cell Interactions in Tissue Homeostasis and Fibrosis**

Antony Rosen, MD
Vice Dean for Research, Mary Betty Stevens Professor of Medicine 

Livia Casciola-Rosen, PhD
Professor of Medicine

Scott Zeger, PhD
Professor and Vice Provost for Research

Johns Hopkins University School of Medicine

 

 

 

Scleroderma Lung Disease Trajectory Study**

Kathryn Torok, MD
Assistant Professor

Anne Stevens, MD, PhD
Associate Professor, Department of Pediatrics

University of Pittsburgh School of Medicine

University of California Washington School of Medicine

Identification of Novel Pathogenic Genes in Juvenile Systemic Sclerosis**
Michael Whitfield, PhD
Associate Professor of Genetics
Dartmouth Medical School A Gene Expression Map of Scleroderma

Fredrick Wigley, MD
Professor of Medicine, Associate Director of the Division of Rheumatology, Director of the Johns Hopkins Scleroderma Center

Francesco Boin, MD
Associate Professor of Medicine

In collaboration with:

Dan Kastner, MD, PhD
Scientific Director

Johns Hopkins University School of Medicine

 

 

University of California, San Francisco

 

National Human Genome Research Institute

Genomic Research in African American Scleroderma Patients (GRASP)
Fredrick Wigley, MD
Professor of Medicine, Associate Director of the Division of Rheumatology, Director of the Johns Hopkins Scleroderma Center
Johns Hopkins University School of Medicine The Johns Hopkins Scleroderma Center of Excellence
*Includes projects approved for inclusion in 2017 portfolio, but funded in FYE2018 **Indicates new addition to project portfolio