Vascular remodeling in pulmonary arterial hypertension: Multiple cancer-like pathways and possible treatment modalities

Author: Seiichiro Sakao and Koichiro Tatsumia
Date Published: August-2010
Source: International Journal of Cardiology

Most patients with severe pulmonary arterial hypertension (PAH) demonstrate persistent structural alterations in small pulmonary arterioles at the time of diagnosis, including marked proliferation of pulmonary artery endothelial cells (ECs), smooth muscle cells (SMCs) and fibroblasts.


AddThis Social Bookmark Button