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Author: Debendra Pattanaik, Arnold E. Postlethwaite Date Published: August-2010 Source: Discovery Medicine
Systemic sclerosis (SSc) is a complex fibrosing autoimmune disease that has variable clinical manifestations and morbidity/mortality secondary to organ damage due to vasculopathy and/or fibrosis. Initial events in the pathogenesis are manifested by fibroproliferative vasculopathy that compromises delivery of blood to critical organs.
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