Response to self antigen imprints regulatory memory in tissues

Author: M. Rosenblum, I. Gratz, J. Paw, K. Lee, A. Marshak-Rothstein & A. Abbas
Date Published: November-2011
Source: Nature

Immune homeostasis in tissues is achieved through a delicate balance between pathogenic T-cell responses directed at tissue-specific antigens and the ability of the tissue to inhibit these responses. The mechanisms by which tissues and the immune system communicate to establish and maintain immune homeostasis are currently unknown.


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