Gender and ethnicity differences in the prevalence of scleroderma-related autoantibodies.

Author: Krzyszczak ME, Li Y, Ross SJ, et al
Date Published: October-2011
Source: Journal of Cellular and Molecular Medicine

Autoantibodies to topoisomerase I (topo I), RNA polymerase III (RNAPIII), centromere, U3RNP/fibrillarin, Th, PM-Scl, and U1RNP found in scleroderma (SSc) are associated with unique clinical subsets. The effects of race and gender on autoantibody prevalence and clinical manifestations were examined.


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