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Author: J. Wei, F. Fang, A. Lam, J. Sargent, et al Date Published: February-2012 Source: Arthritis & Rheumatism
Fibrosis in human diseases and animal models is associated with aberrant Wnt/β-catenin pathway activation. The regulation, activity, mechanism of action and significance of Wnt/β-catenin signaling in the context of systemic sclerosis (SSc) has not been characterized.
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