Possible single-nucleotide polymorphism Loci associated with systemic sclerosis susceptibility: a genetic association study in a chinese han population.

Author: Shu C, Du W, Mao X, et al
Date Published: December-2014
Source: PLOS One

A total of 248 SSc patients and 251 healthy controls of Chinese Han ethnicity, which visited the department of dermatology of Peking Union Medical College Hospital, were included in the study. Six selected single nucleotide polymorphisms (SNPs) in the RHOB and FAM167A-BLK regions were selected as markers and were genotyped using a MassARRAY system, which is based on the matrix-assisted laser desorption/ionization time of flight mass spectrometry technique.