Scleroderma
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  • Research
    • Funded Research
    • Fellowship Program
    • Research News
      • Screening for PAH in Systemic Sclerosis: Does It Matter?
      • Stimulation of soluble guanylate cyclase reduces experimental dermal fibrosis
      • Emerging patterns of genetic overlap across autoimmune disorders.
      • An Evaluation of Long-Term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From REVEAL.
      • Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype.
      • Elevated expression of cav-1 in a subset of SSc fibroblasts contributes to constitutive Alk1/Smad1 activation.
      • Work productivity in scleroderma: Analysis from the University of California, Los Angeles scleroderma quality of life study
      • Mechanism, Potential Therapy for Scleroderma Lung Disease Uncovered
      • Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-alpha treatment
      • Left ventricular dysfunction assessed by speckle-tracking strain analysis in patients with systemic sclerosis: relationship to functional capacity and ventricular arrhythmias.
      • Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers
      • NEFA/nucleobindin-2 is a target autoantigen of the anti-Wa antibody and is associated with transfer RNA.
      • Haemopoietic stem-cell transplantation for systemic sclerosis
      • Emerging targeted therapies in scleroderma lung and skin fibrosis.
      • Anti-PM-Scl antibody in patients with systemic sclerosis.
      • Response to self antigen imprints regulatory memory in tissues
      • Agreement with Guidelines from a Large Database for Management of Systemic Sclerosis: Results from the Canadian Scleroderma Research Group.
      • Warfarin in Systemic Sclerosis-associated and Idiopathic Pulmonary Arterial Hypertension. A Bayesian Approach to Evaluating Treatment for Uncommon Disease.
      • Methotrexate and Corticosteroids in the Treatment of Localized Scleroderma: A Standardized Prospective Longitudinal Single-center Study
      • Gender and ethnicity differences in the prevalence of scleroderma-related autoantibodies.
      • Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry.
      • Thoracic manifestations of collagen vascular diseases.
      • SSc in 2011: From mechanisms to medicines
      • Analysis of extracellular superoxide dismutase in fibroblasts from patients with systemic sclerosis.
      • Unraveling the genetic component of systemic sclerosis.
      • An Update on the Evaluation and Management of Pulmonary Hypertension in Scleroderma.
      • Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
      • The impact of cardio-pulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies.
      • Cytokine modulation by endothelin-1 and possible therapeutic implications in systemic sclerosis.
      • Circulating fibrocytes and pulmonary arterial hypertension
      • Polymorphisms in the Interleukin 4, Interleukin 13, and Corresponding Receptor Genes Are Not Associated with Systemic Sclerosis and Do Not Influence Gene Expression
      • Association Between Thr21Met and Ser89Asn Polymorphisms of the Urotensin II Gene and Systemic Sclerosis
      • Localized expression of tenascin in systemic sclerosis–associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3
      • Analysis of extracellular superoxide dismutase in fibroblasts from patients with systemic sclerosis.
      • Combination Therapy in Pulmonary Arterial Hypertension: A Meta-Analysis.
      • Dendritic Cells: Novel Players in Fibrosis and Scleroderma
      • More Research News
    • Scientific Advisory Board
      • Bruce Alberts, PhD (Chair)
      • David Botstein, PhD
      • Shaun R. Coughlin, MD, PhD
      • Dan Kastner, MD, PhD
      • Regis B. Kelly, PhD
      • Henry Metzger, MD
      • Antony Rosen, MD
      • William J. Rutter, PhD
      • Bruce U. Wintroub, MD
      • George Yancopoulos, MD, PhD
      • Closing Text
    • Grant Guidelines and Applications
      • Post-doctoral Fellowship Guidelines
      • Research Application Guidelines
  • About Us
    • History
    • Board of Directors
      • BOD - Luke Evnin
      • BOD - Kristen Baker Bellamy
      • BOD - Dana Delany
      • BOD - Susan Feniger
      • BOD - Jeff Mace
      • BOD - Bob Saget
      • BOD - Deann Wright
      • BOD - Caryn Zucker
    • Scientific Advisory Board
      • Bruce Alberts, PhD (Chair)
      • David Botstein, PhD
      • Shaun R. Coughlin, MD, PhD
      • Dan Kastner, MD, PhD
      • Regis B. Kelly, PhD
      • Henry Metzger, MD
      • Antony Rosen, MD
      • William J. Rutter, PhD
      • Bruce U. Wintroub, MD
      • George Yancopoulos, MD, PhD
      • Closing Text
    • Annual Report
      • Annual Report - 2011
      • Annual Report - 2010
      • Annual Report - 2009
    • SRF in the News
      • SRF Insights eNewsletter
      • Celebrities give back: Bob Saget's Scleroderma Gala and Fortune Society Fall Benefit
      • Ashley Olsen Reunites With Bob Saget For a Special Charity Evening
      • NHGRI selects new scientific director for intramural research
      • Susan Feniger Plays for SRF on Top Chef Masters - Her Finale Episode
      • Cool Comedy-Hot Cuisine Los Angeles "On The Red Carpet"
      • Susan Feniger's "Touchdown" on Top Chef Masters
      • Susan Feniger: How I Made It In Los Angeles
      • America's Funniest Fundraiser-Bob Saget
      • Andy Richter Takes Round One of the Jeopardy! Celebrity Invitational
      • New round of 'Celebrity Jeopardy' begins
      • Cool Comedy - Hot Cuisine scleroderma benefit
      • At Fundraiser, Housewives Creator Dishes on Finale
      • Robin Williams talks seriously about scleroderma
    • Downloads
      • Annual Report - 2011
      • Sharing the Spotlight: Celebrity Heroes
      • Moving Forward
  • Get Involved
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    • Cool Comedy – Hot Cuisine
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  • Cure Crew
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  • For Patients
    • News for Patients
      • Screening for PAH in Systemic Sclerosis: Does It Matter?
      • Emerging patterns of genetic overlap across autoimmune disorders.
      • An Evaluation of Long-Term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From REVEAL.
      • Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype.
      • Mechanism, Potential Therapy for Scleroderma Lung Disease Uncovered
      • Epidemiology of systemic sclerosis: incidence, prevalence, survival, risk factors, malignancy, and environmental triggers
      • Work productivity in scleroderma: Analysis from the University of California, Los Angeles scleroderma quality of life study
      • Haemopoietic stem-cell transplantation for systemic sclerosis
      • Emerging targeted therapies in scleroderma lung and skin fibrosis.
      • 32 Million Americans Have Autoantibodies That Target Their Own Tissues
      • Methotrexate and Corticosteroids in the Treatment of Localized Scleroderma: A Standardized Prospective Longitudinal Single-center Study
      • New NIH center translates research into real-world use
      • SSc in 2011: From mechanisms to medicines
      • Pulmonary hypertension in kids differs from adult PAH
      • Top 10 Medical Research Trends to Watch in 2012
      • Unraveling the genetic component of systemic sclerosis.
      • Preterm Delivery a Risk in Systemic Sclerosis
      • An Update on the Evaluation and Management of Pulmonary Hypertension in Scleroderma.
      • Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities
      • The impact of cardio-pulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies.
      • Commonly Used Blood Pressure Drug Prevents Smoking-Related Lung Damage in Mice
      • New Uses for Existing Medicines
      • Pulmonary complications of childhood rheumatic disease.
      • Successful pregnancies but a higher risk of preterm births in systemic sclerosis: An Italian multicentric study
      • Environmental triggers and epigenetic deregulation in autoimmune disease.
      • Scleroderma Mimics
      • Gastrointestinal Manifestations of Scleroderma: Recent Progress in Evaluation, Pathogenesis, and Management
      • NIH establishes National Center for Advancing Translational Sciences
      • Genetics of Systemic Sclerosis: An Update
      • Sex differences and genomics in autoimmune diseases.
      • Winter Weather Skin Conditions: The Trifecta
      • International Journal of Rheumatology - Systemic Sclerosis Annual Special Issue
      • A decade of achievement in pulmonary hypertension
      • American College of Rheumatology - Simple Tasks Video Series
      • How To Look And Feel Beautiful With Autoimmune Disease
      • Application of Biomarkers to Clinical Trials in Systemic Sclerosis.
      • Formula Calculates Need for Heart Catheterization in SSc
      • More Patient News
    • What is scleroderma
    • Frequently Asked Questions
    • Risk Factors
    • Tips for Living
    • Clinical Trials
    • Current Treatments
      • Treatment News
      • Archived Treatment News
    • Treatment Centers
    • Additional Resources
    • Webinars
  • For Physicians
    • Current Treatments
    • Treatment Centers
    • News for Physicians
      • Appropriate Screening, Diagnosis, and Management of PAH: Revealing and Addressing Treatment Gaps
      • Please Don't Shake My Hand
      • Pain Perspective in Scleroderma
      • 2011 Video Lecture - Advances in Scleroderma Treatement
      • Diagnosis and Treatment of Scleroderma-Related PAH: Improving Patient Care and Outlook
      • Scleroderma-Related PAH: The Need for Early Diagnosis and Treatment
      • Lung involvement in systemic sclerosis
      • Pathogenesis of the Raynaud phenomenon
      • Treatment of Pulmonary Hypertension
      • Nonpharmacologic therapy for the Raynaud phenomenon
      • 2010 FESCA Video Lecture - Renal complications of systemic sclerosis
      • 2010 FESCA Video Lecture - Cardiovascular Issues in Scleroderma
      • 2010 FESCA Video Lecture - Raynaud's Phenomenon
      • Prognosis and treatment of interstitial lung disease in systemic sclerosis (scleroderma)
      • Targeted Treatment for Rheumatic Diseases, 1st Edition Systemic Sclerosis and Raynaud’s Phenomenon
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The Scleroderma Research Foundation is a 501(c)3 nonprofit organization whose mission is to fund and facilitate the most promising medical research aimed at improved therapies and, ultimately, a cure for scleroderma. Information provided by the SRF should not be considered medical advice, nor is it intended to replace consultation with a qualified physician. The SRF does not evaluate, endorse or recommend any particular medications, products, equipment or treatments. Scleroderma varies substantially from one patient to another, and treatment must be tailored by a physician for each individual case.